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Article

Activation of pericentromeric and telomeric heterochromatin in cultured lymphocytes from old individuals.

Annals of the New York Academy of Sciences - 1 Apr 2007

Lezhava Teimuraz, Jokhadze Tina

Abstract excerpt

The functional characteristics of chromosomes (level of total heterochromatin, chromosome instability, and sister chromatid exchanges [SCEs]) were studied in cultured lymphocytes derived from 80- to 91-year-old and 18- to 30-year-old (control group) individuals under the single and combined effect of CoCl(2) and bioregulator Livagen. The results obtained showed that chromosome heterochromatinization (condensation...

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Identifiers

PMID: 17460203
DOI: 10.1196/annals.1395.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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