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Article

Alpha-1-antitrypsin deficiency: a review; 1963-1975.

Annals of clinical and laboratory science - 1 Jan 2000

Heidelberger K P

Abstract excerpt

Alpha-1-antitrypsin (A1AT) deficiency originally was recognized as a biochemical abnormality in patients with pulmonary emphysema. Studies of the protein nature of A1AT during attempts to help explain the disease, led to the recognition of a protein polymorphism which expressed itself in several...

Topics

Deficiency Diseases
Female
Humans
Liver Cirrhosis
Male
Phenotype
Polymorphism, Genetic
Pulmonary Emphysema
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1108756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1108756-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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