Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mortality rates among carriers of ataxia-telangiectasia mutant alleles.

Annals of internal medicine - 21 Nov 2000

Su Y, Swift M

Abstract excerpt

BACKGROUND: Mutations at the ataxia-telangiectasia locus cause a distinctive autosomal recessive syndrome in homozygotes and predispose heterozygotes to cancer and ischemic heart disease. OBJECTIVE: To examine mortality rates among persons carrying a mutated ataxia-telangiectasia gene. DESIGN: Retrospective cohort study. SETTING: The United States and Canada. PARTICIPANTS: 405 grandparents of patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia
Share to Cause of Death
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Data Interpretation, Statistical

Share to Heterozygote

Share to Myocardial Ischemia

Share to Neoplasms

Share to Risk Factors

Source

Identifiers

PMID: 11085839
DOI: 10.7326/0003-4819-133-10-200011210-00009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mortality rates among carriers of ataxia-telangiectasia mutant alleles.PMID 11085839Read ↗

Health risks for ataxia-telangiectasia mutated heterozygotes: a systematic review, meta-analysis and evidence-based guideline.Semantic proximity Read ↗

Incidence of Cancer in 161 Families Affected by Ataxia–TelangiectasiaSemantic proximity Read ↗

Morbidity and mortality from ataxia-telangiectasia are associated with ATM genotype.Semantic proximity Read ↗

Cancer in patients with ataxia-telangiectasia and in their relatives in the nordic countries.Semantic proximity Read ↗

Breast cancer incidence and the effect of cigarette smoking in heterozygous carriers of mutations in the ataxia-telangiectasia gene.Semantic proximity Read ↗

A late onset variant of ataxia-telangiectasia with a compound heterozygous genotype, A8030G/7481insA.Semantic proximity Read ↗

The natural history of ataxia-telangiectasia (A-T): A systematic review.Semantic proximity Read ↗

Cancer susceptibility in ataxia-telangiectasia.Semantic proximity Read ↗

Cancer risks and mortality in heterozygous ATM mutation carriers.Semantic proximity Read ↗

[Ataxia telangiectasia and genetic predisposition to cancer].Semantic proximity Read ↗

Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer.Semantic proximity Read ↗

Genotype–phenotype correlations in ataxia telangiectasia patients with ATM c.3576G>A and c.8147T>C mutationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.