Article
Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity.
Cancer research - 1 Nov 2000
Lebedeva I, Rando R, Ojwang J, Cossum P, Stein C A
Abstract excerpt
Both Bcl-xL and Bcl-2, antiapoptotic members of the Bcl family, are found in prostate cancer cell lines. Although these proteins may have similar antiapoptotic functions, it is not clear to what extent each serves as an antiapoptotic effector in prostate cancer cells. We engineered LNCaP and PC-3...
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