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Article

FemABX Family Members Are Novel Nonribosomal Peptidyltransferases and Important Pathogen-specific Drug Targets

1 Mar 2001

Abstract excerpt

Pathogen-specific antibiotics kill the offending species without inviting the patient's flora to help develop a resistance mechanism. The current scarcity of pathogen-specific antibiotics reflects the rarity of essential genes that are also not widely represented in and conserved among species. The FemX enzyme that initiates the synthesis of the interchain peptide of the peptidoglycan in a subset of bacterial...

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Share to Antibiotic Resistance in Bacteria
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11083873
DOI: 10.1074/jbc.m008591200

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