Article
[Calcium channels and migraine].
Pathologie-biologie - 1 Sept 2000
Couraud F, Seagar M
Abstract excerpt
Familial hemiplegic migraine is a hereditary form of migraine in which the aura includes a certain degree of motor deficit. A first gene responsible for this disease was located on chromosome 19 in 1993, and identified in 1996. It encodes the principal alpha 1-subunit of a potential-dependent calcium channel, the P/Q channel, which is selectively expressed in the nervous system. This channel is particularly rich...
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