Article
Specific mutation in exon 11 of c-kit proto-oncogene in a malignant gastrointestinal stromal tumor of the rectum.
Journal of gastroenterology - 1 Jan 2000
Yamaguchi M, Miyaki M, Iijima T, Matsumoto T, Kuzume M, Matsumiya A, Endo Y, Sanada Y, Kumada K
Abstract excerpt
Gastrointestinal stromal tumor (GIST) in the distal third of the rectum was detected in a 57-year-old man who underwent an abdominoperineal resection of the rectum. Because the tumor expressed CD34 and c-kit gene product, but did not express smooth muscle actin or S-100 protein, it was diagnosed...
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