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Article

Routine addition of human insulin-like growth factor-I ligand could benefit clinical in-vitro fertilization culture

1 Nov 1998

Abstract excerpt

Animal studies suggest that the insulin-like growth factors play an important role in preimplantation embryo development. Human preimplantation embryos express mRNA for insulin-like growth factor-I receptor (IGF-IR) but the ligand, insulin-like growth factor-I (IGF-I), is not expressed by the embryo until after implantation. We tested the hypothesis that IGF-I produced by the female reproductive tract may bind to...

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Share to Growth Hormone and Insulin-like Growth Factors
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PMID: 9853872
DOI: 10.1093/humrep/13.11.3144

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