Article
Genomic events in the adenoma to carcinoma sequence.
Seminars in gastrointestinal disease - 1 Oct 2000
Terdiman J P
Abstract excerpt
Owing to its high incidence and anatomical accessibility, colorectal cancer has become the most extensively studied human neoplasm with respect to molecular pathogenesis. Many of the genomic alterations that occur when a normal colonic epithelial cell gradually is transformed into a malignant cell have been well characterized. An understanding of the molecular basis of colorectal cancer will lead to better cancer...
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