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Article

BRCA1 and BRCA2 mutations in central and southern Italian patients.

Breast cancer research : BCR - 1 Jan 2000

Ottini L, D'Amico C, Noviello C, Lauro S, Lalle M, Fornarini G, Colantuoni O A, Pizzi C, Cortesi E, Carlini S, Guadagni F, Bianco A R, Frati L, Contegiacomo A, Mariani-Costantini R

Abstract excerpt

Protein truncation test (PTT) and single-strand conformation polymorphism (SSCP) assay were used to scan the BRCA1 and BRCA2 genes in 136 unrelated Italian breast/ovarian cancer patients. In the sample tested, BRCA1 and BRCA2 equally contributed to site-specific breast cancer patients who reported one to two breast cancer-affected first-/ second-degree relative(s) or who were diagnosed before age 40 years in the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 11056688
DOI: 10.1186/bcr72
PMCID: PMC13918

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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