Article
BRCA1 and BRCA2 genes: role in hereditary breast and ovarian cancer in Italy.
International journal of cancer - 24 Sept 1999
Santarosa M, Dolcetti R, Magri M D, Crivellari D, Tibiletti M G, Gallo A, Tumolo S, Della Puppa L, Furlan D, Boiocchi M, Viel A
Abstract excerpt
The heritable defects of BRCA1 and BRCA2 genes have been shown to predispose to breast and ovarian cancers. In a previous report, we analyzed 46 Italian families with breast and/or ovarian cancer for BRCA1 mutations. In the present study, those families and 11 others were screened for BRCA2 mutat...
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