Article
Evolution of hepatitis B virus polymerase gene mutations in hepatitis B e antigen-negative patients receiving lamivudine therapy.
Hepatology (Baltimore, Md.) - 1 Nov 2000
Lok A S, Hussain M, Cursano C, Margotti M, Gramenzi A, Grazi G L, Jovine E, Benardi M, Andreone P
Abstract excerpt
Lamivudine has been shown to be effective in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B, but its long-term efficacy and the rate of resistant mutations in patients with HBeAg-negative chronic hepatitis B is less clear. Twenty-nine patients with HBeAg-negative chronic hepatitis B, who have received lamivudine for at least 1 year were studied to determine the antiviral response, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.