Article
The population genetics of ecological specialization in evolving Escherichia coli populations.
Nature - 12 Oct 2000
Cooper V S, Lenski R E
Abstract excerpt
When organisms adapt genetically to one environment, they may lose fitness in other environments. Two distinct population genetic processes can produce ecological specialization-mutation accumulation and antagonistic pleiotropy. In mutation accumulation, mutations become fixed by genetic drift in genes that are not maintained by selection; adaptation to one environment and loss of adaptation to another are caused...
Topics
- Adaptation, Physiological
- Ecology
- Escherichia coli
- Evolution, Molecular
- Genes, Bacterial
- Glucose
- Models, Biological
- Mutation