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Article

Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome.

Pediatric research - 1 Nov 2000

Sago H, Carlson E J, Smith D J, Rubin E M, Crnic L S, Huang T T, Epstein C J

Abstract excerpt

Two animal models of Down syndrome (human trisomy 21) with segmental trisomy for all (Ts65Dn) or part (Ts1Cje) of human chromosome 21-homologous region of mouse chromosome 16 have cognitive and behavioral abnormalities. To compare these trisomies directly and to assess the phenotypic contribution of the region of difference between them, Ts65Dn, Ts1Cje, and a new segmental trisomic (Ms1Ts65) for the region of...

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Source

Identifiers

PMID: 11044479
DOI: 10.1203/00006450-200011000-00009

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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