Article
Functional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr.
Journal of virology - 1 Nov 2000
Singh S P, Tomkowicz B, Lai D, Cartas M, Mahalingam S, Kalyanaraman V S, Murali R, Srinivasan A
Abstract excerpt
Vpr, encoded by the human immunodeficiency virus type 1 genome, contains 96 amino acids and is a multifunctional protein with features which include cell cycle arrest at G(2), nuclear localization, participation in transport of the preintegration complex, cation channel activity, oligomerization, and interaction with cellular proteins, in addition to its incorporation into the virus particles. Recently,...
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