Article
[Relationship between polymorphism C677T of the methylene tetrahydrofolate reductase gene with clinical symptoms of coronary atherosclerosis].
Genetika - 1 Sept 2000
Spiridonova M G, Stepanov V A, Pyzyrev V P, Karpov R S
Abstract excerpt
Association of the methylenetetrahydrofolate reductase gene (MTHFR) C677T missense mutation (substitution of cytosine by thymine at position 677) with coronary artery disease (CAD), as well as with blood levels of various lipoprotein fractions, systolic pressure (SP), diastolic arterial blood pressures (DP), and body mass index (BMI) in patients with angiographically verified CAD and in a control group. The...
Topics
- Blood Pressure
- Body Mass Index
- Cholesterol
- Coronary Artery Disease
- Genotype
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Mutation
- Oxidoreductases Acting on CH-NH Group Donors
- Polymorphism, Genetic