Article
[Relationship between methylenetetrahydrofolate reductase gene polymorphism and coronary heart disease].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Oct 1998
Chen B, Wang X, Yu J, Zhang G, Chen F, Den J, Fu S, Li P, Cao W, Yu H
Abstract excerpt
OBJECTIVE: This study inquired into the relationship between methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and coronary heart disease. METHODS: By polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP), MTHFR 677C-->T mutation was detected in 79 healthy controls and 69 patients with coronary heart disease. RESULTS: The frequency of MTHFR variant V677 of patients was...
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