Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Origin and persistence of the mitochondrial genome.

Human reproduction (Oxford, England) - 1 Jul 2000

Jansen R P

Abstract excerpt

The mitochondrial genome comprises a circular, histone-free 'chromosome' of 16.6 kb of DNA, present in one or more copies in every mitochondrion. This chromosome has been tightly conserved for more than half a billion years, coding in every multicellular animal so far investigated, both vertebrate and invertebrate: (i) the same 13 protein subunits required for oxidative phosphorylation; (ii) a component of each...

Topics

Animals
DNA, Mitochondrial
Evolution, Molecular
Extrachromosomal Inheritance
Genome
Humans
Mitochondria
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11041508
DOI: 10.1093/humrep/15.suppl_2.1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Origin and persistence of the mitochondrial genome.PMID 11041508Read ↗

The incomplete natural history of mitochondria.Semantic proximity Read ↗

Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.Semantic proximity Read ↗

Transmission, inheritance and replication of mitochondrial DNA in mammals: implications for reproductive processes and infertilitySemantic proximity Read ↗

Evolution and maintenance of mtDNA gene content across eukaryotesSemantic proximity Read ↗

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease.Semantic proximity Read ↗

Mitochondrial genetics revisited.Semantic proximity Read ↗

Mitochondrial genome maintenance in health and disease.Semantic proximity Read ↗

Mammalian mitochondrial genetics: heredity, heteroplasmy and disease.Semantic proximity Read ↗

Evolutionary defined role of the mitochondrial DNA in fertility, disease and ageing.Semantic proximity Read ↗

Evolutionary origin and consequences of uniparental mitochondrial inheritance.Semantic proximity Read ↗

Inheritance of mitochondrial DNA in humans: implications for rare and common diseases.Semantic proximity Read ↗

What cost mitochondria? The maintenance of functional mitochondrial DNA within and across generations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.