Article
Origin and persistence of the mitochondrial genome.
Human reproduction (Oxford, England) - 1 Jul 2000
Jansen R P
Abstract excerpt
The mitochondrial genome comprises a circular, histone-free 'chromosome' of 16.6 kb of DNA, present in one or more copies in every mitochondrion. This chromosome has been tightly conserved for more than half a billion years, coding in every multicellular animal so far investigated, both vertebrate and invertebrate: (i) the same 13 protein subunits required for oxidative phosphorylation; (ii) a component of each...
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