Article
Genetic factors determine extent of bone loss in inflammatory bowel disease.
Gastroenterology - 1 Oct 2000
Schulte C M, Dignass A U, Goebell H, Röher H D, Schulte K M
Abstract excerpt
BACKGROUND & AIMS: Although bone loss and osteoporosis are well-known long-term sequelae of inflammatory bowel disease (IBD), the risk factors for increased bone loss have not been identified. Balances of pro- and anti-inflammatory cytokines influence mechanisms of both chronic inflammation and bone resorption. The aim of this study was to identify genetic risk factors for rapid bone loss in IBD patients as a...
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