Article
The phosphatidylethanolamine-binding protein is the prototype of a novel family of serine protease inhibitors.
The Journal of biological chemistry - 5 Jan 2001
Hengst U, Albrecht H, Hess D, Monard D
Abstract excerpt
Serine proteases are involved in many processes in the nervous system and specific inhibitors tightly control their proteolytic activity. Thrombin is thought to play a role in tissue development and homeostasis. To date, protease nexin-1 is the only known endogenous protease inhibitor that specifically interferes with thrombotic activity and is expressed in the brain. In this study, we report the detection of a...
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