Article
Effects of dietary folate on intestinal tumorigenesis in the apcMin mouse.
Cancer research - 1 Oct 2000
Song J, Medline A, Mason J B, Gallinger S, Kim Y I
Abstract excerpt
Dietary folate appears to be inversely related to colorectal cancer risk. This study investigated the effects of dietary intervention with folate or the development of intestinal polyps in Min (Apc +/-) mice. Weanling Mil mice were fed diets containing 0, 2 (basal requirement), 8, or 20 mg folate/kg diet. At 3 and 6 months of dietary intervention, 50% of the mice from each group were sacrificed, and the small...
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