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Identification of a point mutation in the voltage‐gated sodium channel gene of Kenyan <i>Anopheles gambiae</i> associated with resistance to DDT and pyrethroids

1 Oct 2000

Abstract excerpt

A field trial of permethrin-impregnated bednets and curtains was initiated in Western Kenya in 1990, and a strain of Anopheles gambiae showing reduced susceptibility to permethrin was colonized from this site in 1992. A leucine-phenylalanine substitution at position 1014 of the voltage-gated sodium channel is associated with resistance to permethrin and DDT in many insect species, including Anopheles gambiae from...

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PMID: 11029667
DOI: 10.1046/j.1365-2583.2000.00209.x

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