Article
The Drosophila broad-complex regulates developmental changes in transcription and chromatin structure of the 67B heat-shock gene cluster.
Journal of molecular biology - 19 Aug 1994
Dubrovsky E B, Dretzen G, Bellard M
Abstract excerpt
At the end of the third larval instar of Drosophila, ecdysone triggers the tissue-specific activation of gene expression. In cytogenetic and molecular studies, the Broad-complex (BR-C) locus has been defined as a key element in the hierarchy of hormonal regulation of gene activity. Here we show t...
Topics
- Animals
- Base Sequence
- Chromatin
- Drosophila melanogaster
- Genes, Insect
- Genes, Regulator
- Heat-Shock Proteins
- Larva
- Male
- Molecular Sequence Data
- Multigene Family
- Mutation
- RNA, Messenger
- Salivary Glands
- Transcription, Genetic