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Article

HLA-B27 transgenic rats are susceptible to accelerated alveolar bone loss.

Journal of periodontology - 1 Sept 2000

Tatakis D N, Guglielmoni P

Abstract excerpt

BACKGROUND: HLA-B27 transgenic rats exhibit generalized, severe inflammatory reactions and spontaneously develop arthritis and chronic gastrointestinal inflammation, as well as inflammatory lesions in other tissues. Our hypothesis was that HLA-B27 rats would also be susceptible to inflammatory periodontal disease, and therefore alveolar bone loss. The purpose of this investigation was to compare the naturally...

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Share to Alveolar Bone Loss
Share to Animals, Genetically Modified
Share to Genes, MHC Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-B27 Antigen

Share to Rats, Inbred F344

Share to Reproducibility of Results

Share to Specific Pathogen-Free Organisms

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Source

Identifiers

PMID: 11022768
DOI: 10.1902/jop.2000.71.9.1395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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