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Article

Genetic variation in LMNA modulates plasma leptin and indices of obesity in aboriginal Canadians.

Physiological genomics - 29 Jun 2000

Hegele R A, Cao H, Harris S B, Zinman B, Hanley A J, Anderson C M

Abstract excerpt

We previously showed that a rare mutation in LMNA, which encodes lamins A and C, underlies autosomal dominant Dunnigan-type familial partial lipodystrophy (FPLD). Because FPLD is an extreme example of genetically disturbed adipocyte differentiation, it is possible that common variation in LMNA is associated with obesity-related phenotypes. We therefore analyzed the relationships between the common LMNA 1908T/C...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11015599
DOI: 10.1152/physiolgenomics.2000.3.1.39

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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