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Article

Effects of arsenite on estrogen receptor-alpha expression and activity in MCF-7 breast cancer cells.

Endocrinology - 1 Oct 2000

Stoica A, Pentecost E, Martin M B

Abstract excerpt

To determine whether arsenite has estrogen-like activities, the effects of this compound on estrogen receptor-alpha (ERalpha) and other estrogen-regulated genes were measured in the human breast cancer cell line MCF-7. Treatment of cells with 1 microM arsenite resulted in a 60% decrease in the amount of ERalpha and in a parallel decrease of 40% in ERalpha messenger RNA. Progesterone receptor concentration...

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Source

Identifiers

PMID: 11014213
DOI: 10.1210/endo.141.10.7704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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