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Article

Evolution of Microbial Genomics: Conceptual Shifts over a Quarter Century.

Trends in microbiology - 1 Jul 2021

Koonin Eugene V, Makarova Kira S, Wolf Yuri I

Abstract excerpt

Prokaryote genomics started in earnest in 1995, with the complete sequences of two small bacterial genomes, those of Haemophilus influenzae and Mycoplasma genitalium. During the next quarter century, the prokaryote genome database has been growing exponentially, with no saturation in sight. For most of these 25 years, genome sequencing remained limited to cultivable microbes. Together with next-generation...

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Identifiers

PMID: 33541841
DOI: 10.1016/j.tim.2021.01.005
PMCID: PMC9404256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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