Article
C677T mutation of the methylenetetrahydrofolate reductase gene among the Korean infants in Seoul city.
The Kobe journal of medical sciences - 1 Dec 1999
Zuo M, Lee M J, Kim M H, Wu Y, Ayaki H, Nishio H, Sumino K
Abstract excerpt
The missense mutation, C677T (Ala--->Val), in the methylenetetrahydrofolate reductase (MTHFR) gene, is related to hyperhomocysteinemia and is regarded as a risk factor for coronary artery disease and neural tube defects. The prevalence of this mutation was reported to differ among various ethnic groups, but there are few reports concerning Asian populations. We have investigated the frequencies of C677T mutation...
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