Article
[The induction of the antitumor activity of T-lymphocytes by antigen-presenting cells obtained from the blast cells of patients with acute leukemias].
Terapevticheskii arkhiv - 1 Jan 2000
Savchenko V G, Sadovnikova E Iu, Parovichnikova E N, Mendeleeva L P, Demidova I A, Sokolov A N, Isaev V G
Abstract excerpt
AIM: To produce antigen-presenting cells (APC) from tumor cells of patients with acute leukemia and to induce autologous cytotoxic tumor-specific T-lymphocytes in vivo and in vitro. MATERIAL AND METHODS: Culture examinations, flow cytofluorometry were made in 3 patients with acute myeloid leukemia (AML) and 1 patient with acute lymphoblastic leukemia (ALL). RESULTS: Culturing of blast cells in the presence of...
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