Article
T lymphocytes of allophenic mice do not reject spleen colony-forming units of the parental genotypes.
Journal of hematotherapy & stem cell research - 1 Aug 2000
Fedorov L M, Panteleev E I
Abstract excerpt
Self-tolerance in BALB/c<-->C57BL/6 and BALB/c<-->B10.SM (SM) allophenic mice is examined in this study. Chimerism was determined by coat mosaicism, using electrophoresis of allozyme variants at the glucose phosphate isomerase-1 (GPI-1) in peripheral blood erythrocytes and a cytotoxity test for lymph node (LN) lymphocytes and blood nucleated cells. An age-dependent increase in the percent content of BALB/c...
Topics
- Animals
- Bone Marrow Transplantation
- Chimera
- Colony-Forming Units Assay
- Female
- Genotype
- Immune Tolerance
- Lymph Nodes
- Lymphocyte Transfusion
- Male
- Mice
- Mice, Inbred BALB C
