Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sulfa or sulfone prophylaxis and geographic region predict mutations in the Pneumocystis carinii dihydropteroate synthase gene.

The Journal of infectious diseases - 1 Oct 2000

Huang L, Beard C B, Creasman J, Levy D, Duchin J S, Lee S, Pieniazek N, Carter J L, del Rio C, Rimland D, Navin T R

Abstract excerpt

To determine factors associated with mutations in the Pneumocystis carinii dihydropteroate synthase (DHPS) gene, a prospective study of human immunodeficiency virus (HIV)-infected patients with confirmed P. carinii pneumonia was conducted in Atlanta, Seattle, and San Francisco. Clinical information was obtained from patient interview and chart abstraction. DHPS genotype was determined from DNA sequencing....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AIDS-Related Opportunistic Infections
Share to Dihydropteroate Synthase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Georgia

Share to Pneumocystis

Share to Pneumonia, Pneumocystis

Share to Racial Groups

Share to San Francisco

Share to Washington

Source

Identifiers

PMID: 10979917
DOI: 10.1086/315824

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sulfa or sulfone prophylaxis and geographic region predict mutations in the Pneumocystis carinii dihydropteroate synthase gene.PMID 10979917Read ↗

Pneumocystis carinii dihydropteroate synthase genotypes in HIV-infected persons residing in San Francisco: possible implications for disease transmission.Semantic proximity Read ↗

Dihydropteroate synthase polymorphisms in Pneumocystis carinii.Semantic proximity Read ↗

Increase in prevalence of Pneumocystis carinii mutations in patients with AIDS and P. carinii pneumonia, in the United States and China.Semantic proximity Read ↗

Detection of Pneumocystis carinii and characterization of mutations associated with sulfa resistance in bronchoalveolar lavage samples from human immunodeficiency virus-infected subjects.Semantic proximity Read ↗

Mutations in the dihydropteroate synthase gene of human-derived Pneumocystis carinii isolates from Italy are infrequent but correlate with prior sulfa prophylaxis.Semantic proximity Read ↗

Pneumocystis carinii mutations are associated with duration of sulfa or sulfone prophylaxis exposure in AIDS patients.Semantic proximity Read ↗

Rapid detection of mutations in the human-derived Pneumocystis carinii dihydropteroate synthase gene associated with sulfa resistance.Semantic proximity Read ↗

Sulfa use, dihydropteroate synthase mutations, and Pneumocystis jirovecii pneumonia.Semantic proximity Read ↗

Pneumocystis carinii dihydropteroate synthase but not dihydrofolate reductase gene mutations correlate with prior trimethoprim-sulfamethoxazole or dapsone use.Semantic proximity Read ↗

Sulfa resistance and dihydropteroate synthase mutants in recurrent Pneumocystis carinii pneumonia.Semantic proximity Read ↗

Genetic variation in Pneumocystis carinii isolates from different geographic regions: implications for transmission.Semantic proximity Read ↗

Pneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in immunocompromised patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.