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Epstein‐Barr Virus Gene Expression in the Peripheral Blood of Transplant Recipients with Persistent Circulating Virus Loads

1 Oct 2000

Abstract excerpt

Pediatric solid organ transplant recipients are at risk for Epstein-Barr virus (EBV)-driven lymphoproliferative disease. The expression of 5 sentinel EBV genes (EBNA1, EBNA2a, LMP1, LMP2a, and ZEBRA) was examined in solid organ transplant recipients who developed persistent virus loads in their peripheral blood lymphocytes after transplantation. Two distinct groups were identified. LMP2a gene expression alone was...

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PMID: 10979894
DOI: 10.1086/315828

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