Article
Fork head prevents apoptosis and promotes cell shape change during formation of the Drosophila salivary glands.
Development (Cambridge, England) - 1 Oct 2000
Myat M M, Andrew D J
Abstract excerpt
The secretory tubes of the Drosophila salivary glands are formed by the regulated, sequential internalization of the primordia. Secretory cell invagination occurs by a change in cell shape that includes basal nuclear migration and apical membrane constriction. In embryos mutant for fork head (fkh), which encodes a transcription factor homologous to mammalian hepatocyte nuclear factor 3beta (HNF-3beta), the...
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