Article
Mutations in the human delta-sarcoglycan gene in familial and sporadic dilated cardiomyopathy.
The Journal of clinical investigation - 1 Sept 2000
Tsubata S, Bowles K R, Vatta M, Zintz C, Titus J, Muhonen L, Bowles N E, Towbin J A
Abstract excerpt
Dilated cardiomyopathy (DCM) is a major cause of morbidity and mortality. Two genes have been identified for the X-linked forms (dystrophin and tafazzin), whereas three other genes (actin, lamin A/C, and desmin) cause autosomal dominant DCM; seven other loci for autosomal dominant DCM have been mapped but the genes have not been identified. Hypothesizing that DCM is a disease of the cytoskeleton and sarcolemma,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.