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Article

ε-Sarcoglycan, a Broadly Expressed Homologue of the Gene Mutated in Limb-Girdle Muscular Dystrophy 2D

1 Dec 1997

Abstract excerpt

The sarcoglycans are transmembrane components of the dystrophin-glycoprotein complex, which links the cytoskeleton to the extracellular matrix in adult muscle fibers. Mutations in all four known sarcoglycan genes (alpha, beta, gamma, and delta) have been found in humans with limb-girdle muscular dystrophy. We have identified a novel protein, epsilon-sarcoglycan, that shares 44% amino acid identity with...

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Identifiers

PMID: 9405466
DOI: 10.1074/jbc.272.51.32534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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ε-Sarcoglycan, a Broadly Expressed Homologue of the Gene Mutated in Limb-Girdle Muscular Dystrophy 2DPMID 9405466Read ↗

Human epsilon-sarcoglycan is highly related to alpha-sarcoglycan (adhalin), the limb girdle muscular dystrophy 2D gene.Semantic proximity Read ↗

zeta-Sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophySemantic proximity Read ↗

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ε-Sarcoglycan Replaces α-Sarcoglycan in Smooth Muscle to Form a Unique Dystrophin-Glycoprotein ComplexSemantic proximity Read ↗

Beta-sarcoglycan: characterization and role in limb-girdle muscular dystrophy linked to 4q12.Semantic proximity Read ↗

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