Article
Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.
Biochemical and biophysical research communications - 7 Sept 2000
Pratt W S, Crawley S, Hicks J, Ho J, Nash M, Kim Y S, Gum J R, Swallow D M
Abstract excerpt
The MUC3 gene encodes a transmembrane mucin-type glycoprotein. A number of consistent single nucleotide changes were observed in different MUC3 cDNAs from a single individual, suggesting the presence of at least three different transcripts per individual. This transcript heterogeneity is due both to the existence of a second copy of the MUC3 gene and to allelic changes. Sequencing of the second MUC3 shows that it...
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