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Article

Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia

1 Jan 2000

Abstract excerpt

The purpose of this study was to investigate the role of fas antigen, a member of the TNF receptor family, in cell death after focal cerebral ischemia. Focal ischemia was induced in the Sprague-Dawley rat. Evidence for apoptosis was determined by morphology as well as the presence of DNA fragmentation by the end labeling technique (TUNEL). Immunohistochemistry was performed to detect expression of both fas and...

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PMID: 10972965
DOI: 10.1002/1097-4547(20000915)61:6<686::aid-jnr12>3.0.co;2-7

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