Article
Antigenic diversity of Plasmodium falciparum and antibody-mediated parasite neutralization.
Scandinavian journal of immunology - 1 Sept 2000
Bolad A, Berzins K
Abstract excerpt
The malaria parasite Plasmodium falciparum, causing the most severe form of the disease in humans, is characterized by a broad antigenic diversity between different strains and isolates of the parasite. The antigenic diversity reflects on the one hand polymorphisms in allelic gene products and, on the other hand, antigenic variation as a result of expression of alternative genes in multigene families. Using...
Topics
- Adult
- Animals
- Antibodies, Protozoan
- Antigenic Variation
- Antigens, Protozoan
- Child
- Erythrocytes
- Genotype
- Host-Parasite Interactions
- Humans
- Malaria Vaccines
- Malaria, Falciparum
