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Article

Follow-up of chimerism status after allogeneic HLA-mismatched stem cell transplantation by detection of non-shared HLA alleles.

Haematologica - 1 Aug 2000

Gallardo D, Rodríguez-Luaces M, Aróstegui J I, Ferrá C, Berlanga J J, Querol S, García-López J, Grañena A

Abstract excerpt

BACKGROUND AND OBJECTIVES: Chimerism studies after allogeneic transplantation are usually performed using cytogenetic analysis, PCR-VNTR or PCR-STR. Here, we report an alternative method for following the chimerism status after an HLA-mismatched stem cell transplantation (SCT), detecting the presence of non-shared HLA alleles by reference-strand mediated conformation analysis (RSCA). DESIGN AND METHODS: We tested...

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PMID: 10942932

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SCT

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