Article
Homozygosity for a conserved Mhc class II DQ-DRB haplotype is associated with rapid disease progression in simian immunodeficiency virus-infected macaques: results from a prospective study.
The Journal of infectious diseases - 1 Sept 2000
Sauermann U, Stahl-Hennig C, Stolte N, Mühl T, Krawczak M, Spring M, Fuchs D, Kaup F J, Hunsmann G, Sopper S
Abstract excerpt
In human immunodeficiency virus type 1 (HIV-1)-infected individuals, disease progression varies considerably. This is also observed after experimental infection of macaques with simian immunodeficiency virus (SIV). Major histocompatibility complex (MHC) genes may influence disease progression in both species. Homozygosity for Mhc-Mamu (Macaca mulatta)-DQB1*0601 was previously identified to be associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.