Article
Mycobacteria-macrophage interactions. Macrophage phenotype determines the nonopsonic binding of Mycobacterium tuberculosis to murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 1993
Stokes R W, Haidl I D, Jefferies W A, Speert D P
Abstract excerpt
During tuberculosis, host defenses may be determined, in part, by the capacity of resident, elicited, and activated macrophages to bind and ingest Mycobacterium tuberculosis. We have investigated the mechanism by which macrophages bind M. tuberculosis and other mycobacteria in a serum-free system...
Topics
- Animals
- Antibodies, Monoclonal
- Binding Sites
- Female
- In Vitro Techniques
- Macrophage Activation
- Macrophages
- Mice
- Mice, Inbred BALB C
- Mycobacterium tuberculosis
- Opsonin Proteins
- Phagocytosis
- Phenotype
- Receptors, Complement
- Tetradecanoylphorbol Acetate
- Tuberculosis
- Zymosan