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Article

Epistasis and the conversion of non-additive to additive genetic variance at population bottlenecks.

Theoretical population biology - 1 Aug 2000

López-Fanjul C, Fernández A, Toro M A

Abstract excerpt

The effect of population bottlenecks on the mean and the additive variance generated by two neutral independent epistatic loci has been studied theoretically. Six epistatic models, used in the analysis of binary disease traits, were considered. Ancestral values in an infinitely large panmictic population were compared with their expectations at equilibrium, after t consecutive bottlenecks of equal size N (derived...

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Identifiers

PMID: 10944475
DOI: 10.1006/tpbi.2000.1470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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