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Article

The action of stabilizing selection, mutation, and drift on epistatic quantitative traits.

Evolution; international journal of organic evolution - 1 Jul 2014

Avila Victoria, Pérez-Figueroa Andrés, Caballero Armando, Hill William G, García-Dorado Aurora, López-Fanjul Carlos

Abstract excerpt

For a quantitative trait under stabilizing selection, the effect of epistasis on its genetic architecture and on the changes of genetic variance caused by bottlenecking were investigated using theory and simulation. Assuming empirical estimates of the rate and effects of mutations and the intensity of selection, we assessed the impact of two-locus epistasis (synergistic/antagonistic) among linked or unlinked loci...

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Source

Identifiers

PMID: 24689841
DOI: 10.1111/evo.12413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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