Article
Cell biology. Sowing the protein seeds of prion propagation.
Science (New York, N.Y.) - 28 Jul 2000
Tuite M F
Abstract excerpt
Ever since Prusiner first proposed his radical "protein-only" hypothesis to explain how certain infectious proteins (prions) are transmitted from one mammal to another in the absence of DNA or RNA, scientists have been trying to prove him right (or wrong). The study of mammalian prions, such as those causing Creutzfeldt-Jakob disease in humans, scrapie in sheep and mad cow disease in cattle, has been slow to...
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