Article
In vivo and in vitro assessment of the virulence of Listeria monocytogenes strains.
The new microbiologica - 1 Jul 2000
Gattuso A, Gianfranceschi M, Sessa R, Taggi F, Pourshaban M, Aureli P
Abstract excerpt
To evaluate whether the in vitro model (invasion and intracellular growth in Caco-2 cells) for determining virulence is a suitable alternative to the in vivo model (50% lethal dose), we compared the levels of virulence obtained with the two models. We tested L. monocytogenes strains isolated from food and clinical samples during three episodes of listeriosis occurring in Italy in the period 1993-1995. We also...
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