Article
Application of flow cytometry to the diagnosis of paroxysmal nocturnal hemoglobinuria.
Cytometry - 15 Aug 2000
Richards S J, Rawstron A C, Hillmen P
Abstract excerpt
Within the contemporary multitude of complex methods used in clinical flow cytometry, very few techniques exist which can be described as disease-specific diagnostic tests. Detection of glycophosphatidylinositol (GPI)-linked antigens on hematopoietic cells using monoclonal antibodies and flow cytometry forms the basis of a specific diagnostic test for paroxysmal nocturnal hemoglobinuria (PNH). Absent or markedly...
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