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Role of Human Cytomegalovirus Immediate-Early Proteins in Cell Growth Control

1 Sept 2000

Abstract excerpt

Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that has been implicated in several disorders, including an association between HCMV reactivation and the overproliferation of arterial smooth muscle cells observed in restenosis. Although HCMV can mediate a growth-arrest phenotype in infected cells, the virus can also promote an environment conducive to proliferation. Here, we present evidence that the...

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PMID: 10933712
DOI: 10.1128/jvi.74.17.8028-8037.2000

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