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Transforming growth factor-β1 in the developing mouse pancreas: a potential regulator of exocrine differentiation

1 Jun 2000

Abstract excerpt

Transforming growth factor-beta 1 (TGF-beta 1) is known to regulate cell growth, differentiation, and function in developing mammalian systems. Altering TGF-beta 1 expression in the developing pancreas has been shown to affect both exocrine and endocrine development, suggesting that it is an important regulator of pancreatic organogenesis. We proposed to examine the ontogeny of TGF-beta 1 mRNA expression in the...

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PMID: 10929204
DOI: 10.1046/j.1432-0436.2000.6550255.x

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