Article
Cross-talk between orientation-dependent recognition determinants of a complex control RNA element, the enterovirus oriR.
RNA (New York, N.Y.) - 1 Jul 2000
Melchers W J, Bakkers J M, Bruins Slot H J, Galama J M, Agol V I, Pilipenko E V
Abstract excerpt
The coxsackie B3 virus oriR is an element of viral RNA thought to promote the assembly of a ribonucleoprotein complex involved in the initiation of genome replication. The mutual orientation of its two helical domains X and Y is determined by a kissing interaction between the loops of these domains. Here, a genetic approach was worked out to identify spatial orientation-dependent recognition signals in these...
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