Article
Coreceptor restriction within the HLA-DQ locus for Epstein-Barr virus infection.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 2000
Haan K M, Longnecker R
Abstract excerpt
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that causes infectious mononucleosis and is etiologically associated with malignancies of multiple origins. EBV enters cells through a cascade of interactions between its envelope glycoprotein gp350 and the gp42-gH-gL complex with cellular receptors. Membrane fusion is catalyzed by the binding of gp42, a member of the C type lectin family, to HLA class II...
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